"Don't ever underestimate the power of ‘We The People!’" said Christine O'Donnell, Republican Senate Candidate for Delaware.
The Tea Party favorite, who Republicans said, “couldn't be elected dogcatcher," won the party's Senate nomination in Delaware.
In New York, political newcomer Carl Paladino overcame his challenger's 40-point lead to become the Republicans' candidate for Governor.
"If we've learned anything tonight it's that New Yorkers are as mad as hell," said Paladino.
He'll take on Democrat Andrew Cuomo.
Also in New York, 40-year veteran Charlie Rangel beat five other Democrats and a dozen ethics charges in his bid to stay in Washington.
"No matter what they say, I go back to Washington stronger than I've ever been! “ said Rangel.
In all, five states chose Senate nominees and six more named candidates for Governor. Democrats are hoping to hold on to their majority.
House Speaker Nancy Pelosi said, "I am not yielding one grain of sand."
In D.C.’s Mayor's race, local Council Chair Vince Gray led Mayor Adrian Fenty by nearly 9-thousand votes.
"Tonight the people of the District sent a message loud and clear that they want to bring character, integrity and leadership back to Mayor's office!" said Gray.
And that may be the final word. There's no Republican running against him this fall.